
Palmetto Endocrinology
Endocrinology • Summerville, SC • Since 2014
About
Palmetto Endocrinology is a private endocrinology practice in Summerville, SC, with a second location in Ladson. Led by Dr. Joseph Mathews, the clinic specializes in endocrine, thyroid, and diabetes care, offering services for weight loss, PCOS, Hashimoto’s, adrenal and parathyroid disorders, male hypogonadism, and related conditions. They perform office-based ultrasound-guided procedures (ECNU-certified) and may host clinical trials to provide access to the latest treatments. The practice serves patients from across the region, including out-of-state referrals, and operates from two South Carolina offices. Contact: multiple local phone lines are available.
Clinic Type
Endocrinology
Address
1101 Old Trolley Road #300, Summerville, SC 29485; 3496 Iron Horse Road, Ladson, SC 29456
Phone
8433762670
—
Opening Hours
Not published — contact the clinic to confirm hours.
Services Offered
Technology & Equipment
Team
Insurance & Payment
—
We accept most major insurance plans
Languages Spoken
—
Photos








What Patients Say
Overall sentiment across review platforms: mixed
- Official Practice Website: 4.89 out of 5 stars (based on their internal testimonial count) (122 (internal website count))
- WebMD: 5.0 (based on 7 reviews) (7)
- Yelp: Not specified numerically (12)
Patients praise
- Dr. Joseph Mathews is frequently praised for his expertise, clinical knowledge, and life-changing care for complex conditions like thyroid cancer and rare disorders
- Patients appreciate the doctor's willingness to listen and spend time during consultations
- Successful treatment outcomes reported by some patients
Common complaints
- Rudeness and lack of professionalism from front office staff
- Difficulty reaching the office via phone or getting timely responses to messages
- Long wait times for appointments and administrative delays (e.g., lab orders, medication refills)
- Frustration with being handed off to Physician Assistants/Nurse Practitioners instead of the lead physician
"Dr. Mathews, as others have said, has saved and changed my life... He is so knowledgeable and kind. I trust him completely."
— Doctor.com Review"The doctors are good and the staff are friendly but they really need more help with answering the phone. I have called at several different times of the day and no one ever picks up... It’s ridiculous."
— LocalityBiz Review"The front office staff are extremely rude and make all interactions feel like a bother. The worst, and most unacceptable part, is I often run out of medication."
— Healthgrades ReviewSynthesized from public review platforms as of Jul 11, 2026 — sources: [1][2][3][4].
In the News
Information sourced from the clinic's website as of . Own this clinic? Claim or correct this listing.
Related articles
- Top 6 Vascular Surgeons in Virginia: 2026 Selection Criteria — Oct 26, 2026
- 5 Best Eye Doctors and Ophthalmologists in Maine — Oct 25, 2026
- 5 Best Orthodontists in Michigan by Treatment Fit — Oct 21, 2026
Comparing your options?
See other endocrinology clinics in Summerville, or search the full directory by insurance, ratings, and more.

